Natural Progesterone Cream 60g


Natpro is an aqueous cream made exclusively of vegetable based ingredients. It is supplied in tubes, each of which contains 60 grams (2 oz) of cream. Natpro has a concentration of 3.33% or 33.33 milligrams per gram. Each tube is sufficient for one month at the start of use. Although Natpro is supplied in single tubes research has established that for the majority of people the full benefits may only be realised after 3 months use. Please bear this in mind when using and purchasing.

Each dispenser of Natpro contains:

           de-ionised water

           caprylic/capric triglyceride

           cetearyl olivate/sorbitan olivate

           progesterone Ph. Eur. USP. JP.

           populus tremuloides

           dehydroxanthan gum

           vitamin E


*Ecocert approval for use in natural and organic skin care


De-ionized water - this is an industry standard for water purification


Caprylic/capric triglycerides is a medium chain triglyceride of fractionated vegetable fatty acids extracted from coconuts. It is colourless, neutral in odour and taste, and has a very low viscosity. It has very good resistance to oxidation. It serves as a carrier and transport vehicle for active ingredients, as it penetrates the skin readily, being easily absorbed. It does not leave a greasy film and helps to retain moisture.


Progesterone Ph. Eur. USP JP - is derived principally from stigmasterol, a steroidal sapogenin. Phytosterols are chemically similar to cholesterol which is found in animals. Cholesterol is the starting point for the hormones made naturally in animals, including humans. Plants such as the soy bean, Dioscorea species of yams, fenugreek, sisal, calabar bean, some lilies, yucca, some solanum species, maize and many more contain phytosterols, some of which are stigmasterol, diosgenin, sitosterol, campesterol, hecogenin, smilagenin, sarsasapogenin, solasodine. As these sterols have a similar molecular structure to progesterone, they are used as starting points for the synthesis of progesterone.


Cetearyl olivate/sorbitan olivate - a unique natural PEG-free organic emulsifier from olive oil. It reduces skin water loss, has a high moisturizing effect, is hypoallergenic and biomimics the skin.


Populus tremuloides - a natural preservative made from non GM aspen trees. ‘Aspen bark extract’ as such is a unique discovery,  as it is an effective natural replacement for commonly used harmful chemical preservatives. It also improves the emollience (the 'feel good' factor) of the cream.


dl-alpha tocopherol - vitamin E - all emulsions made with vegetable oils have the potential to go rancid. For this reason dl-alpha tocopherol is used as it’s an in vitro antioxidant.


Natpro does not contain:

           animal derivatives | mineral oils | colorants | scents | synthetic antioxidants | synthetic preservatives

Natpro is not tested on animals. 

Natpro has a pH which is in balance with the skin and can be used by anyone with a dietary or environmental concern.


When and how much Natpro to use

The cream can be used at any time of the day and, if preferred, on more than one occasion, but no less than twice a day, as progesterone levels drop after about 13 hours. It can be applied to any part of the body and does not have to be used only on the thin skinned areas as is sometimes recommended. The skin comprises 95% kerotinocytes, which have a plentiful supply of progesterone receptors, even the hair follicles absorb it well. 

Please note the amount suggested is a guide only as each individual is different. It’s only by trial and error that the correct amount is found. Another point to remember is that stress drops progesterone levels sharply so apply more to prevent the return of symptoms.


Progesterone should always be used dependant on symptoms and not on ‘dose’. If symptoms are severe more will be needed, if mild then less.


Generally between 100-200mg/day of progesterone (that is 3ml to 6ml of cream) is needed.




If a cycle is present apply the cream twice daily from ovulation for the next 14 days, bleeding should occur within a day or two. The luteal phase is always 12-14 days in all women, any less and it’s known as a ‘defective luteal phase’ Cycles vary from 21 days to 36 days. For instance in a 21 day cycle the cream should be used from day 8 for 14 days, if a 28 day cycle from day 15 for 14 days, and if a 36 day cycle from day 22 for 14 days.


Peri or post Menopausal, Hysterectomy, Oophorectomy, Pre-pubertal, Pubertal 

If there is no cycle, or an erratic one too difficult to follow, apply the cream twice daily. There is no need for a break as some suggest, although some women prefer to have one. Either is fine.


Severe symptoms

Hot flushes - Use at least 400mg/day for 4-5 days, this generally stops them. It’s best to apply the cream hourly.

Heavy, continual bleeding - 400-600mg/day from 1 to 3 months, ignoring the cycle. When the bleeding has stopped, slowly reduce the cream until bleeding occurs again, then discontinue the cream for 14 days. Then start again from day 15 for 14 days. Over the coming months the natural cycle length will assert itself. It’s best to apply the cream hourly.

A multitude of bad symptoms - Use a minimum of 200mg/day following the cycle, more might be needed. If symptoms return during the break, then continue applying the cream twice daily or more frequently until they resolve. Once they have then begin following the cycle again.



Use from 10 to 100mg/day of progesterone (that is 0.3ml to 3 ml of cream). It’s best applied twice a day. For further advice on how to use it please click here 


Supplemental progesterone can initially make a person more sensitive to the oestrogen in their body. Because of this, oestrogen dominance may occur which can be very disconcerting. The following is a short list of what can be encountered...

breast tenderness | bloating/weight gain from water retention | spotting or a temporary reappearance of your periods | headaches/ migraines/ dizziness | hypoglycaemia | aches and pains or bruising | depression | tiredness/chronic fatigue | hot flushes | mood swings | anger | skin problems | nausea


Before using Natpro, it is important to read more by clicking here

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NATPRO Natural Progesterone Cream 60g

  • Product Code: NATPRO Natural Progesterone Cream 60ml
  • Availability: In Stock
  • £28.00